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Microneedles are newly developed biomedical devices, whose advantages are mainly in the non-invasiveness, discretion and versatility of use both as diagnostics and as therapeutics tool. In fact, they can be used both for drugs delivery in the interstitial fluids and for the analysis of the interstitial fluid. In this work we present the preliminary results for two devices based on micro needles in PolyEthylene (Glycol). The first for the drugs delivery includes a membrane whose optical reflected wavelength is related to the concentration of drug. Here, we present our preliminary result in diffusion of drugs between the membrane and the microneedles. The second device is gold coated and it works as electrode for the electrochemical detection of species in the interstitial fluid. A preliminary result in detection of glucose will be shown.
International Society for Optics and Photonics
Publication date: 
1 Jun 2015

P Dardano, A Calio, J Politi, V Di Palma, MF Bevilacqua, I Rea, M Casalino, A Di Matteo, I Rendina, L De Stefano

Biblio References: 
Volume: 9518 Pages: 95180L
Bio-MEMS and Medical Microdevices II